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Proceedings Paper

Bone optical spectroscopy for the measurement of hemoglobin content
Author(s): Joseph L Hollmann; Paula Arambel; Judith Piet; Sandra Shefelbine; Stacey Markovic; Mark Niedre; Charles A. DiMarzio
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Paper Abstract

Osteoporosis is a common side effect of spinal cord injuries. Blood perfusion in the bone provides an indication of bone health and may help to evaluate therapies addressing bone loss. Current methods for measuring blood perfusion of bone use dyes and ionizing radiation, and yield qualitative results. We present a device capable of measuring blood oxygenation in the tibia. The device illuminates the skin directly over the tibia with a white light source and measures the diffusely reflected light in the near infrared spectrum. Multiple source-detector distances are utilized so that the blood perfusion in skin and bone may be differentiated.

Paper Details

Date Published: 19 May 2014
PDF: 3 pages
Proc. SPIE 9155, Translational Biophotonics, 91551L (19 May 2014); doi: 10.1117/12.2060716
Show Author Affiliations
Joseph L Hollmann, Northeastern Univ (United States)
Paula Arambel, Northeastern Univ. (United States)
Judith Piet, Univ. de Technologie de Compiègne (France)
Sandra Shefelbine, Northeastern Univ. (United States)
Stacey Markovic, Northeastern Univ. (United States)
Mark Niedre, Northeastern Univ. (United States)
Charles A. DiMarzio, Northeastern Univ. (United States)


Published in SPIE Proceedings Vol. 9155:
Translational Biophotonics
Tomasz S. Tkaczyk, Editor(s)

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