In-situ detection of DNA hybridization with a microfiber Bragg grating biosensor | (2014) | Sun | Publications

Proceedings Paper

In-situ detection of DNA hybridization with a microfiber Bragg grating biosensor

Author(s): Dandan Sun; Tuan Guo; Xiaodong Xie; Yang Ran; Yunyun Huang; Bai-Ou Guan

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Paper Abstract

Microfiber Bragg gratings (mFBGs) can be used as cost-effective and relatively simple-to-implement biosensors for monitoring DNA interactions in situ. The sensors are functionalized by a monolayer of poly-L-lysine (PLL) with the specific molecular recognition probe DNA sequences to bind with high specificity to a given target. By recording the wavelength seperation between the two resonant peaks of a single mFBG, the mFBG biosensor is capable of detecting the presence of specific target DNA in situ.

Paper Details

Date Published: 2 June 2014
PDF: 4 pages
Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91574Z (2 June 2014); doi: 10.1117/12.2059433

Show Author Affiliations

Dandan Sun, Jinan Univ. (China)
Tuan Guo, Jinan Univ. (China)
Xiaodong Xie, Jinan Univ. (China)

Yang Ran, Jinan Univ. (China)
Yunyun Huang, Jinan Univ. (China)
Bai-Ou Guan, Jinan Univ. (China)

Published in SPIE Proceedings Vol. 9157:
23rd International Conference on Optical Fibre Sensors
José M. López-Higuera; Julian D. C. Jones; Manuel López-Amo; José Luis Santos, Editor(s)