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Proceedings Paper

Celiac disease biodetection using lossy-mode resonances generated in tapered single-mode optical fibers
Author(s): A. B. Socorro; J. M. Corres; I. Del Villar; I. R. Matias; F. J. Arregui
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Paper Abstract

This work presents the development and test of an anti-gliadin antibodies biosensor based on lossy mode resonances (LMRs) to detect celiac disease. Several polyelectrolites were used to perform layer-by-layer assembly processes in order to generate the LMR and to fabricate a gliadin-embedded thin-film. The LMR shifted 20 nm when immersed in a 5 ppm anti-gliadin antibodies-PBS solution, what makes this bioprobe suitable for detecting celiac disease. This is the first time, to our knowledge, that LMRs are used to detect celiac disease and these results suppose promising prospects on the use of such phenomena as biological detectors.

Paper Details

Date Published: 2 June 2014
PDF: 4 pages
Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91573J (2 June 2014); doi: 10.1117/12.2059254
Show Author Affiliations
A. B. Socorro, Univ. Pública de Navarra (Spain)
J. M. Corres, Univ. Pública de Navarra (Spain)
I. Del Villar, Univ. Pública de Navarra (Spain)
I. R. Matias, Univ. Pública de Navarra (Spain)
F. J. Arregui, Univ. Pública de Navarra (Spain)


Published in SPIE Proceedings Vol. 9157:
23rd International Conference on Optical Fibre Sensors
José M. López-Higuera; Julian D. C. Jones; Manuel López-Amo; José Luis Santos, Editor(s)

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