Share Email Print
cover

Proceedings Paper

Polarimetric fiber grating biosensor for in-situ high-sensitive intracellular density measurement
Author(s): Tuan Guo; Fu Liu; Yu Liu; Nan-Kuang Chen; Bai-Ou Guan; Jacques Albert
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

High sensitivity biological sample measurements have been achieved by using a 12o tilted fiber Bragg grating (TFBG). Human acute leukemia cells with different intracellular densities and refractive index (RI) ranging from 1.3342 to 1.3344 were clearly discriminated in-situ by using the differential transmission spectrum between two orthogonal polarizations for the last guided mode resonance before “cut-off”, with an amplitude variation sensitivity of 1.8×104 dB/RIU and a limit of detection of 2×10-5 RIU. The technique is inherently temperature-insensitive.

Paper Details

Date Published: 2 June 2014
PDF: 4 pages
Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 915746 (2 June 2014); doi: 10.1117/12.2058465
Show Author Affiliations
Tuan Guo, Jinan Univ. (China)
Fu Liu, Jinan Univ. (China)
Yu Liu, Jinan Univ. (China)
Nan-Kuang Chen, National United Univ. (Taiwan)
Bai-Ou Guan, Jinan Univ. (China)
Jacques Albert, Carleton Univ. (Canada)


Published in SPIE Proceedings Vol. 9157:
23rd International Conference on Optical Fibre Sensors
José M. López-Higuera; Julian D. C. Jones; Manuel López-Amo; José Luis Santos, Editor(s)

© SPIE. Terms of Use
Back to Top