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Proceedings Paper

Wide-field endoscopic fluorescence imaging for gastrointestinal tumor detection with glucose analogue
Author(s): Yun He; Yawei Qu; Jing Bai; Haifeng Liu
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Paper Abstract

The lack of functional information and targeted imaging in conventional white-light endoscopy leads to a high miss-rate of gastrointestinal tumor. The combination of near-infrared fluorescence imaging and endoscopy presents a promising approach. Here we introduce a new endoscopy method employing a home-made flexible wide-field epi-fluorescence endoscope, that can be inserted through the biopsy channel of a gastrointestinal endoscope, with the glucose analogue 2- DeoxyGlucosone as the near-infrared fluorescent probe. System characterization indicates a good sensitivity and linearity over a large field of view. Its capability of tumor identification and location is demonstrated with in-vivo imaging of xenografted tumor model.

Paper Details

Date Published: 19 May 2014
PDF: 4 pages
Proc. SPIE 9155, Translational Biophotonics, 91550R (19 May 2014); doi: 10.1117/12.2057696
Show Author Affiliations
Yun He, Tsinghua Univ. (China)
Yawei Qu, General Hospital of Chinese Armed Police Forces (China)
Jing Bai, Tsinghua Univ. (China)
Haifeng Liu, General Hospital of Chinese Armed Police Forces (China)


Published in SPIE Proceedings Vol. 9155:
Translational Biophotonics
Tomasz S. Tkaczyk, Editor(s)

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