Share Email Print
cover

Proceedings Paper

Spatial resolution analysis for time-domain diffuse optical tomography based on a perturbation model
Author(s): Alexander B. Konovalov; Vitaly V. Vlasov
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

We estimate a limit to spatial resolution in time-domain diffuse optical tomography (DOT) based on a perturbation model by Lyubimov. In the context of structure reconstruction accuracy we consider and compare three approaches to the inverse DOT problem. The first reconstructs diffuse tomograms from straight lines; the second does it from curvilinear average trajectories of photons; and the third uses the total banana-like distributions of photon trajectories. For getting estimates to resolution, we derive analytical expressions for the point spread function and the modulation transfer function, and perform a numerical experiment to reconstruct rectangular scattering objects with circular absorbing inhomogeneities. It is shown that reconstruction with photon trajectory distributions instead of straight lines gives a gain of about order of magnitude in resolution and attains the accuracy of multistep nonlinear DOT algorithms.

Paper Details

Date Published: 30 January 2014
PDF: 12 pages
Proc. SPIE 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV, 903104 (30 January 2014); doi: 10.1117/12.2052831
Show Author Affiliations
Alexander B. Konovalov, Russian Federal Nuclear Ctr. - Zababakhin Institute of Applied Physics (Russian Federation)
Vitaly V. Vlasov, Russian Federal Nuclear Ctr. - Zababakhin Institute of Applied Physics (Russian Federation)


Published in SPIE Proceedings Vol. 9031:
Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV
Elina A. Genina; Vladimir L. Derbov; Igor Meglinski; Valery V. Tuchin, Editor(s)

© SPIE. Terms of Use
Back to Top