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Proceedings Paper

Simultaneous optical manipulation of multiple particles inside microfluidic channels using one rectangular-shaped VCSEL
Author(s): Marwan Bou Sanayeh; Anna Bergmann; Rainer Michalzik
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Paper Abstract

Optical trapping for isolation and sorting of cells and particles inside microfluidic channels is an efficient non-destructive manipulation technique in the field of biophotonics. In recent years, vertical-cavity surface-emitting lasers (VCSELs) have been proven to be excellent light sources for particle manipulation inside microfluidic channels. The small dimension and low power consumption of these devices enable direct integration with the channels. With such integration, however, the simultaneous manipulation or trapping of multiple particles require the usage of densely packed VCSEL arrays with very small device pitch, which makes the fabrication process more expensive and more complicated. We present an innovative technique for simultaneous optical multi-particle manipulation using one rectangular-shaped top-emitting AlGaAsGaAs VCSEL resonator having an active aperture area of around 100 × 14 μm2. The VCSEL emission wavelength is about 850 nm, which is suitable for usage in biophotonics, as biological materials present very little absorption in the near-infrared spectral range. Furthermore, this oblong VCSEL can potentially be integrated with polydimethylsiloxane (PDMS) microfluidic channels to form miniaturized optofluidic chips for ultra-compact particle handling and manipulation. We show efficient single as well as multiple polystyrene particle trapping and sorting inside PDMS microfluidic channels.

Paper Details

Date Published: 8 May 2014
PDF: 7 pages
Proc. SPIE 9129, Biophotonics: Photonic Solutions for Better Health Care IV, 91292O (8 May 2014); doi: 10.1117/12.2051610
Show Author Affiliations
Marwan Bou Sanayeh, Notre Dame Univ., Louaize (Lebanon)
Ulm Univ. (Germany)
Anna Bergmann, Ulm Univ. (Germany)
Rainer Michalzik, Ulm Univ. (Germany)

Published in SPIE Proceedings Vol. 9129:
Biophotonics: Photonic Solutions for Better Health Care IV
Jürgen Popp; Valery V. Tuchin; Dennis L. Matthews; Francesco Saverio Pavone; Paul Garside, Editor(s)

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