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Proceedings Paper

Pulsed excitation system to measure the resonant frequency of magnetoelastic biosensors
Author(s): Hong Xie; Yating Chai; Shin Horikawa; Howard C. Wikle; Bryan A. Chin
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Paper Abstract

An electrical circuit was designed and tested to measure the resonant frequency of micron-scale magnetoelastic (ME) biosensors using a pulsed wave excitation technique. In this circuit, a square pulse current is applied to an excitation coil to excite the vibration of ME biosensors and a pick-up coil is used to sense the ME biosensor’s mechanical vibration and convert it to an electrical output signal. The output signal is filtered and amplified by a custom designed circuit to allow the measurement of the resonant frequency of the ME biosensor from which the detection of specific pathogens can be made. As a proof-in-concept experiment, JRB7 phage-coated ME biosensors were used to detect different concentrations of Bacillus anthracis Sterne strain spores. A statistically significant difference was observed for concentrations of 5 × 102 spore/ml and above.

Paper Details

Date Published: 28 May 2014
PDF: 7 pages
Proc. SPIE 9108, Sensing for Agriculture and Food Quality and Safety VI, 910804 (28 May 2014); doi: 10.1117/12.2049888
Show Author Affiliations
Hong Xie, Auburn Univ. (United States)
Yating Chai, Auburn Univ. (United States)
Shin Horikawa, Auburn Univ. (United States)
Howard C. Wikle, Auburn Univ. (United States)
Bryan A. Chin, Auburn Univ. (United States)

Published in SPIE Proceedings Vol. 9108:
Sensing for Agriculture and Food Quality and Safety VI
Moon S. Kim; Kuanglin Chao, Editor(s)

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