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Proceedings Paper

To the problem of stiffness-contrast quantification in the correlation-stability approach to OCT elastography
Author(s): Lev A. Matveev; Vladimir Yu. Zaitsev; Alexandr L. Matveyev; Grigory V. Gelikonov; Valentin M. Gelikonov
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Paper Abstract

In the initial variant, the recently proposed correlation-stability approach to elasticity mapping in optical coherence tomography (OCT) of tissues was intended for qualitative visualization of the relative stiffness of different regions in tissue. Further development of this approach is aimed at obtaining the stiffness ratio between different tissue regions. In the proposed modified variant, the correlation-stability approach has much in common with the speckle variance approach which is used for visualizing blood microcirculation in OCT. We present preliminary demonstrations of implementation of the modified correlation-stability approach to quantify the relative stiffness using processing of the speckle-structure variability of OCT images of deformed tissues.

Paper Details

Date Published: 30 January 2014
PDF: 6 pages
Proc. SPIE 9031, Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV, 903102 (30 January 2014); doi: 10.1117/12.2049516
Show Author Affiliations
Lev A. Matveev, Institute of Applied Physics (Russian Federation)
Nizhny Novgorod Medical Academy (Russian Federation)
Vladimir Yu. Zaitsev, Institute of Applied Physics (Russian Federation)
Nizhny Novgorod Medical Academy (Russian Federation)
Alexandr L. Matveyev, Institute of Applied Physics (Russian Federation)
Nizhny Novgorod Medical Academy (Russian Federation)
Grigory V. Gelikonov, Institute of Applied Physics (Russian Federation)
Nizhny Novgorod Medical Academy (Russian Federation)
Valentin M. Gelikonov, Institute of Applied Physics (Russian Federation)
Nizhny Novgorod Medical Academy (Russian Federation)


Published in SPIE Proceedings Vol. 9031:
Saratov Fall Meeting 2013: Optical Technologies in Biophysics and Medicine XV; and Laser Physics and Photonics XV
Elina A. Genina; Vladimir L. Derbov; Igor Meglinski; Valery V. Tuchin, Editor(s)

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