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Proceedings Paper

Deep tissue imaging of microfracture and non-displaced fracture of bone using the second and third near-infrared therapeutic windows
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Paper Abstract

Near-infrared (NIR) light in the wavelengths of 700 nm to 2,000 nm has three NIR optical, or therapeutic, windows, which allow for deeper depth penetration in scattering tissue media. Microfractures secondary to repetitive stress, particularly in the lower extremities, are an important problem for military recruits and athletes. They also frequently occur in the elderly, or in patients taking bisphosphonates or denosumab. Microfractures can be early predictors of a major bone fracture. Using the second and third NIR therapeutic windows, we investigated the results from images of chicken bone and human tibial bone with microfractures and non-displaced fractures with and without overlying tissues of various thicknesses. Images of bone with microfractures and non-displaced fractures with tissue show scattering photons in the third NIR window with wavelengths between 1,650 nm and 1,870 nm are diminished and absorption is increased slightly from and second NIR windows. Results from images of fractured bones show the attenuation length of light through tissue in the third optical window to be larger than in the second therapeutic window. Use of these windows may aid in the detection of bone microfractures, and thus reduce the incidence of major bone fracture in susceptible groups.

Paper Details

Date Published: 4 March 2014
PDF: 8 pages
Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89263V (4 March 2014); doi: 10.1117/12.2046706
Show Author Affiliations
Laura A. Sordillo, The City College of the City Univ. of New York (United States)
Yang Pu, The City College of the City Univ. of New York (United States)
P. P. Sordillo, The City College of the City Univ. of New York (United States)
Yury Budansky, The City College of the City Univ. of New York (United States)
Robert R. Alfano, The City College of the City Univ. of New York (United States)


Published in SPIE Proceedings Vol. 8926:
Photonic Therapeutics and Diagnostics X
Bernard Choi; Hyun Wook Kang; Brian J. F. Wong; Guillermo J. Tearney; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory; Justus F. Ilgner; Haishan Zeng; Laura Marcu, Editor(s)

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