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Proceedings Paper

Novel combined fluorescence/reflectance spectroscopy system for guiding brain tumor resections: hardware considerations
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Paper Abstract

Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX concentration under strong ambient light conditions.

Paper Details

Date Published: 18 November 2013
PDF: 9 pages
Proc. SPIE 9032, Biophotonics—Riga 2013, 90320R (18 November 2013); doi: 10.1117/12.2044717
Show Author Affiliations
Zhiyuan Xie, Lund Univ. (Sweden)
Haiyan Xie, Lund Univ. (Sweden)
Monirehalsadat Mousavi, Lund Univ. (Sweden)
Mikkel Brydegaard, Lund Univ. (Sweden)
Johan Axelsson, Lund Univ. (Sweden)
Stefan Andersson-Engels, Lund Univ. (Sweden)


Published in SPIE Proceedings Vol. 9032:
Biophotonics—Riga 2013
Janis Spigulis; Ilona Kuzmina, Editor(s)

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