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Proceedings Paper

Relationship of ultrasound signal intensity with SonoVue concentration at body temperature in vitro
Author(s): Xin Yang; Jing Li; Xiaoling He; Kaizhi Wu; Yun Yuan; Mingyue Ding
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Paper Abstract

In this paper, the relationship between image intensity and ultrasound contrast agent (UCA) concentration is investigated. Experiments are conducted in water bath using a silicon tube filled with UCA (SonoVue) at different concentrations (100μl/l to 6000μl/l) at around 37 °C to simulate the temperature in human body. The mean gray-scale intensity within the region of interest (ROI) is calculated to obtain the plot of signal intensity to UCA concentration. The results show that the intensity firstly exhibits a linear increase to the peak at approximately 1500μl/l then appears a downward trend due to the multiple scattering (MS) effects.

Paper Details

Date Published: 9 April 2014
PDF: 8 pages
Proc. SPIE 9038, Medical Imaging 2014: Biomedical Applications in Molecular, Structural, and Functional Imaging, 903824 (9 April 2014); doi: 10.1117/12.2044395
Show Author Affiliations
Xin Yang, Huazhong Univ. of Science and Technology (China)
Sun Yat-Sen Univ. Cancer Ctr. (China)
Jing Li, Huazhong Univ. of Science and Technology (China)
Qingdao Hisense R&D Ctr. (China)
Xiaoling He, Univ. Hospital, China Univ. of Geosciences (China)
Kaizhi Wu, Huazhong Univ. of Science and Technology (China)
Yun Yuan, Huazhong Univ. of Science and Technology (China)
Mingyue Ding, Huazhong Univ. of Science and Technology (China)


Published in SPIE Proceedings Vol. 9038:
Medical Imaging 2014: Biomedical Applications in Molecular, Structural, and Functional Imaging
Robert C. Molthen; John B. Weaver, Editor(s)

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