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Proceedings Paper

Depth resolution properties of in-line X-ray phase-contrast tomosynthesis
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Paper Abstract

In-line x-ray phase-contrast (XPC) tomosynthesis combines the concepts of tomosynthesis and in-line XPC imaging to utilize the advantages of both for biological imaging applications. Tomosynthesis permits reductions in acquisition times compared with conventional tomography scans while in-line XPC imaging provides high contrast and resolution in images of weakly absorbing materials. In this work, we develop an advanced iterative algorithm as an approach for dealing with the incomplete (and often noisy) data inherent to XPC tomosynthesis. We also investigate the depth resolution properties of XPC tomosynthesis and demonstrate that the z-resolution properties of XPC tomosynthesis is superior to that of conventional absorption-based tomosynthesis. More specifically, we find in-plane structures display strong boundary-enhancement while out-of-plane structures do not. This effect can facilitate the identification of in-plane structures.

Paper Details

Date Published: 19 March 2014
PDF: 7 pages
Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90330H (19 March 2014); doi: 10.1117/12.2044009
Show Author Affiliations
Huifeng Guan, Washington Univ. in St. Louis (United States)
Qiaofeng Xu, Washington Univ. in St. Louis (United States)
Alfred Garson, Washington Univ. in St. Louis (United States)
Mark A. Anastasio, Washington Univ. in St. Louis (United States)

Published in SPIE Proceedings Vol. 9033:
Medical Imaging 2014: Physics of Medical Imaging
Bruce R. Whiting; Christoph Hoeschen, Editor(s)

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