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Proceedings Paper

Spectral lesion characterization on a photon-counting mammography system
Author(s): Klaus Erhard; Erik Fredenberg; Hanno Homann; Ewald Roessl
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Paper Abstract

Spectral X-ray imaging allows to differentiate between two given tissue types, provided their spectral absorption characteristics differ measurably. In mammography, this method is used clinically to determine a decomposition of the breast into adipose and glandular tissue compartments, from which the glandular tissue fraction and, hence, the volumetric breast density (VBD) can be computed. Another potential application of this technique is the characterization of lesions by spectral mammography. In particular, round lesions are relatively easily detected by experienced radiologists, but are often difficult to characterize. Here, a method is described that aims at discriminating cystic from solid lesions directly on a spectral mammogram, obtained with a calibrated spectral mammography system and using a hypothesis-testing algorithm based on a maximum likelihood approach. The method includes a parametric model describing the lesion shape, compression height variations and breast composition. With the maximum likelihood algorithm, the model parameters are estimated separately under the cyst and solid hypothesis. The resulting ratio of the maximum likelihood values is used for the final tissue characterization. Initial results using simulations and phantom measurements are presented.

Paper Details

Date Published: 19 March 2014
PDF: 7 pages
Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90331F (19 March 2014); doi: 10.1117/12.2043028
Show Author Affiliations
Klaus Erhard, Philips Research (Germany)
Erik Fredenberg, Philips Healthcare (Sweden)
Hanno Homann, Philips Research (Germany)
Ewald Roessl, Philips Research (Germany)


Published in SPIE Proceedings Vol. 9033:
Medical Imaging 2014: Physics of Medical Imaging
Bruce R. Whiting; Christoph Hoeschen, Editor(s)

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