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Proceedings Paper

Full field photothermal dynamics microscopy
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Paper Abstract

We present here a novel full field pump-probe photothermal dynamics microscopy (PTDM) which uses a numerical lockin mechanism for capturing full field photothermal responses and is capable of imaging 2D thermal dissipation dynamics by varying the time delay between the probing and pump nano-second pulses. PTDM may find interesting applications in biology and medicine. As one example, we report PTDM imaging nuclei contained on intact hematoxylin and eosin (H&E) stained prostate cancer specimens may potentially be used to distinguish low grade and high grade prostate cancer.

Paper Details

Date Published: 12 March 2014
PDF: 6 pages
Proc. SPIE 8949, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI, 89490X (12 March 2014); doi: 10.1117/12.2042326
Show Author Affiliations
Guichen Tang, Fairfield Univ. (United States)
Fanting Kong, Clemson Univ. (United States)
Y. C. Chen, Hunter College (United States)
M. Xu, Fairfield Univ. (United States)


Published in SPIE Proceedings Vol. 8949:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI
Thomas G. Brown; Carol J. Cogswell; Tony Wilson, Editor(s)

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