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Proceedings Paper

Wavelength, beam size and type dependences of cerebral low-level light therapy: A Monte Carlo study on visible Chinese human
Author(s): Ting Li; Yue Zhao; Meixue Duan; Yunlong Sun; Kai Li
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Paper Abstract

Low level light therapy (LLLT) has been clinically utilized for many indications in medicine requiring protection from cell/tissue death, stimulation of healing and repair of injuries, pain reduction, swelling and inflammation. Presently, use of LLLT to treat stroke, traumatic brain injury, and cognitive dysfunction is attracting growing interest. Near-infrared light can penetrate into the brain tissue, allowing noninvasive treatment to be carried out with few treatment-related adverse events. Optimization of LLLT treatment effect is one key issue of the field; however, only a few experimental tests on mice for wavelength selection have been reported. We addressed this issue by low-cost, straightforward and quantitative comparisons on light dosage distribution in Visible Chinese human head with Monte Carlo modeling of light propagation. Optimized selection in wavelength, beam type and size were given based on comparisons among frequently-used setups (i.e., wavelengths: 660 nm, 810 nm, 980 nm; beam type: Gaussian and flat beam; beam diameter: 2 cm, 4 cm, 6cm).This study provided an efficient way to guide optimization of LLLT setup and selection on wavelength, beam type and size for clinical brain LLLT.

Paper Details

Date Published: 18 February 2014
PDF: 9 pages
Proc. SPIE 8932, Mechanisms for Low-Light Therapy IX, 893209 (18 February 2014); doi: 10.1117/12.2041875
Show Author Affiliations
Ting Li, Univ. of Electronic Science and Technology of China (China)
Yue Zhao, Univ. of Electronic Science and Technology of China (China)
Meixue Duan, Univ. of Electronic Science and Technology of China (China)
Yunlong Sun, Univ. of Electronic Science and Technology of China (China)
Kai Li, Univ. of Electronic Science and Technology of China (China)


Published in SPIE Proceedings Vol. 8932:
Mechanisms for Low-Light Therapy IX
Michael R. Hamblin; James D. Carroll; Praveen Arany, Editor(s)

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