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Proceedings Paper

A model for ultrasound modulated light in a turbid medium
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Paper Abstract

The ability to focus light in most tissue degrades quickly with depth due to high optical scattering. Researchers have investigated using both ultrasound (US) and light synergistically to overcome this difficulty. Ultrasound has been utilized to modulated light within tissue to create a diffusive wave at that is modulated at the US frequency. Recently, there has been interest in the modulated sidebands which reside at optical frequency plus or minus the US frequency. This paper will discuss a model for US-light interactions in a scattering medium. We will use this model to relate the radiance in the probe beam to the radiance in the diffusive wave. We will then employ the P-1 approximation to the radiative transport equation to find the fluence and flux of the modulated wave. We will use these parameters to write a diffusion equation for the modulated wave that can be described in terms of the incoming optical power, and the US intensity and geometry.

Paper Details

Date Published: 12 March 2014
PDF: 8 pages
Proc. SPIE 8949, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI, 89490U (12 March 2014); doi: 10.1117/12.2041179
Show Author Affiliations
Joseph L. Hollmann, Northeastern Univ. (United States)
Gordon Ctr. for Subsurface Sensing and Imaging Systems (United States)
Roarke Horstmeyer, California Institute of Technology (United States)
Changhuei Yang, California Institute of Technology (United States)
Charles A. DiMarzio, Northeastern Univ. (United States)
Gordon Ctr. for Subsurface Sensing and Imaging Systems (United States)


Published in SPIE Proceedings Vol. 8949:
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXI
Thomas G. Brown; Carol J. Cogswell; Tony Wilson, Editor(s)

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