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Proceedings Paper

Differentiating fatty and non-fatty tissue using photoacoustic imaging
Author(s): Leo Pan; Robert Rohling; Purang Abolmaesumi; Septimiu Salcudean; Shuo Tang
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Paper Abstract

In this paper, we demonstrate a temporal-domain intensity-based photoacoustic imaging method that can differentiate between fatty and non-fatty tissues. PA pressure intensity is partly dependent on the tissue’s speed of sound, which increases as temperature increases in non-fatty tissue and decreases in fatty tissue. Therefore, by introducing a temperature change in the tissue and subsequently monitoring the change of the PA intensity, it is possible to distinguish between the two types of tissue. A commercial ultrasound system with a 128-element 5-14 MHz linear array transducer and a tunable ND:YAG laser were used to produce PA images. Ex-vivo bovine fat and porcine liver tissues were precooled to below 10°C and then warmed to room-temperature over ~1 hour period. A thermocouple monitored the temperature rise while PA images were acquired at 0.5°C intervals. The averaged intensity of the illuminated tissue region at each temperature interval was plotted and linearly fitted. Liver samples showed a mean increase of 2.82 %/°C, whereas bovine fat had a mean decrease of 6.24 %/°C. These results demonstrate that this method has the potential to perform tissue differentiation in the temporal-domain.

Paper Details

Date Published: 3 March 2014
PDF: 6 pages
Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 894354 (3 March 2014); doi: 10.1117/12.2041047
Show Author Affiliations
Leo Pan, The Univ. of British Columbia (Canada)
Robert Rohling, The Univ. of British Columbia (Canada)
Purang Abolmaesumi, The Univ. of British Columbia (Canada)
Septimiu Salcudean, The Univ. of British Columbia (Canada)
Shuo Tang, The Univ. of British Columbia (Canada)


Published in SPIE Proceedings Vol. 8943:
Photons Plus Ultrasound: Imaging and Sensing 2014
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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