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Proceedings Paper

Combining 3D optical imaging and dual energy absorptiometry to measure three compositional components
Author(s): Serghei Malkov; John Shepherd
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Paper Abstract

We report on the design of the technique combining 3D optical imaging and dual-energy absorptiometry body scanning to estimate local body area compositions of three compartments. Dual-energy attenuation and body shape measures are used together to solve for the three compositional tissue thicknesses: water, lipid, and protein. We designed phantoms with tissue-like properties as our reference standards for calibration purposes. The calibration was created by fitting phantom values using non-linear regression of quadratic and truncated polynomials. Dual-energy measurements were performed on tissue-mimicking phantoms using a bone densitometer unit. The phantoms were made of materials shown to have similar x-ray attenuation properties of the biological compositional compartments. The components for the solid phantom were tested and their high energy/low energy attenuation ratios are in good correspondent to water, lipid, and protein for the densitometer x-ray region. The three-dimensional body shape was reconstructed from the depth maps generated by Microsoft Kinect for Windows. We used open-source Point Cloud Library and freeware software to produce dense point clouds. Accuracy and precision of compositional and thickness measures were calculated. The error contributions due to two modalities were estimated. The preliminary phantom composition and shape measurements are found to demonstrate the feasibility of the method proposed.

Paper Details

Date Published: 17 February 2014
PDF: 6 pages
Proc. SPIE 8937, Multimodal Biomedical Imaging IX, 893714 (17 February 2014); doi: 10.1117/12.2040903
Show Author Affiliations
Serghei Malkov, Univ. of California, San Francisco (United States)
John Shepherd, Univ. of California, San Francisco (United States)

Published in SPIE Proceedings Vol. 8937:
Multimodal Biomedical Imaging IX
Fred S. Azar; Xavier Intes, Editor(s)

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