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Proceedings Paper

Improved in vivo imaging of human blood circulation in the chorioretinal complex using phase variance method with new phase stabilized 1 μm swept-source optical coherence tomography (pv-SSOCT)
Author(s): Raju Poddar; Dae Yu Kim; John S. Werner; Robert J. Zawadzki
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Paper Abstract

We demonstrate the feasibility of our newly developed phase stabilized high-speed (100 kHz A-scans/s) 1 μm sweptsource optical coherence tomography (SSOCT) system with the phase-variance based motion contrast method for visualization of human chorioretinal complex microcirculation. Compared to our previously reported spectral domain (spectrometer based) phase-variance (pv)-SDOCT system it has advantages of higher sensitivity, reduced fringe washout for high blood flow speeds and deeper penetration in choroid. High phase stability SSOCT imaging was achieved by using a computationally efficient phase stabilization approach. This process does not require additional calibration hardware and complex numerical procedures. Our phase stabilization method is simple and can be employed in a variety of SS-OCT systems. Examples of vasculature in the chorioretinal complex imaged by pv-SSOCT is presented and compared to retinal images of the same volunteers acquired with fluorescein angiography (FA) and indocyanine green angiography (ICGA).

Paper Details

Date Published: 28 February 2014
PDF: 8 pages
Proc. SPIE 8930, Ophthalmic Technologies XXIV, 89300X (28 February 2014); doi: 10.1117/12.2040186
Show Author Affiliations
Raju Poddar, UC Davis Medical Ctr. (United States)
Dae Yu Kim, California Institute of Technology (United States)
John S. Werner, UC Davis Medical Ctr. (United States)
Robert J. Zawadzki, UC Davis Medical Ctr. (United States)
Univ. of California Davis (United States)

Published in SPIE Proceedings Vol. 8930:
Ophthalmic Technologies XXIV
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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