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Proceedings Paper

Photodynamic therapy of cervical intraepithelial neoplasia
Author(s): Natalia Mayumi Inada; Welington Lombardi; Marieli Fernanda Martins Leite; Jose Roberto Trujillo; Cristina Kurachi; Vanderlei Salvador Bagnato
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Paper Abstract

Photodynamic therapy (PDT) is a technique that has been used for the treatment of tumors, especially in Gynecology. The photodynamic reaction is based on the production of reactive oxygen species after the activation of a photosensitizer. Advantages of the PDT in comparison to the surgical resection are: ambulatory treatment and tissue recovery highly satisfactory, through a non-invasive procedure. The cervical intraepithelial neoplasia (CIN) grades I and II presents potential indications for PDT. The aim of the proposed study is to evaluate the safety and efficacy of the PDT for the diagnostics and treatment of CIN I and II. The equipment and the photosensitizer are produced in Brazil with a representative low cost. It is possible to visualize the fluorescence of the cervix and to treat the lesions, without side effects. The proposed clinical protocol shows great potential to become a public health technique.

Paper Details

Date Published: 14 March 2014
PDF: 7 pages
Proc. SPIE 8931, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIII, 89310X (14 March 2014); doi: 10.1117/12.2040004
Show Author Affiliations
Natalia Mayumi Inada, Univ. de São Paulo (Brazil)
Welington Lombardi, Univ. Estadual Paulista (Brazil)
Marieli Fernanda Martins Leite, Univ. Estadual Paulista (Brazil)
Jose Roberto Trujillo, Johns Hopkins Univ. (United States)
Cristina Kurachi, Univ. de São Paulo (Brazil)
Vanderlei Salvador Bagnato, Univ. de São Paulo (Brazil)

Published in SPIE Proceedings Vol. 8931:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIII
David H. Kessel; Tayyaba Hasan, Editor(s)

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