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Proceedings Paper

Analysis of thermal effects in endoscopic nanocarriers-based photodynamic therapy applied to esophageal diseases
Author(s): I. Salas-García; F. Fanjul-Vélez; N. Ortega-Quijano; O. Wilfert; L. Hudcova; J. Poliak; P. Barcik; J. L. Arce-Diego
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Paper Abstract

In this work we propose a predictive model that allows the study of thermal effects produced when the optical radiation interacts with an esophageal or stomach disease with gold nanoparticles embedded. The model takes into account light distribution in the tumor tissue by means of a Monte Carlo method. Mie theory is used to obtain the gold nanoparticles optical properties and the thermal model employed is based on the bio-heat equation. The complete model was applied to two types of tumoral tissue (squamous cell carcinoma located in the esophagus and adenocarcinoma in the stomach) in order to study the thermal effects induced by the inclusion of gold nanoparticles.

Paper Details

Date Published: 26 February 2014
PDF: 6 pages
Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 89410C (26 February 2014); doi: 10.1117/12.2039209
Show Author Affiliations
I. Salas-García, Univ. de Cantabria (Spain)
F. Fanjul-Vélez, Univ. de Cantabria (Spain)
N. Ortega-Quijano, Univ. de Cantabria (Spain)
O. Wilfert, Brno Univ. of Technology (Czech Republic)
L. Hudcova, Brno Univ. of Technology (Czech Republic)
J. Poliak, Brno Univ. of Technology (Czech Republic)
P. Barcik, Brno Univ. of Technology (Czech Republic)
J. L. Arce-Diego, Univ. de Cantabria (Spain)


Published in SPIE Proceedings Vol. 8941:
Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications
E. Duco Jansen; Robert J. Thomas; Gerald J. Wilmink; Bennett L. Ibey, Editor(s)

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