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Proceedings Paper

Spectrum correction considering light source fluctuation for non-invasive blood glucose sensing
Author(s): Satoru Suzuki; Akane Ishida; Pradeep K. W. Abeygunawardhana; Kenji Wada; Akira Nishiyama; Ichiro Ishimaru
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Paper Abstract

The purpose of this study is to correct baseline shift in absorbance spectrums caused by light source fluctuation. To improve quantitative evaluation performance of blood glucose level, baseline shift is corrected by multiple scatter correction (MSC). Moreover, to increase the effect of the MSC, water vapor absorbance is subtracted, and relative glucose absorbance are calculated by dividing with hemoglobin absorbance at 1544 [cm-1]. In order to verify the effectiveness of the proposed spectrum correction method, light source fluctuation is simulated on the Fourier transform infrared spectroscopy (FT-IR), and we apply the proposed method to the spectrums measured by FT-IR. From the simulation results, the baseline shift was successfully reduced by proposed method.

Paper Details

Date Published: 4 March 2014
PDF: 6 pages
Proc. SPIE 8936, Design and Quality for Biomedical Technologies VII, 893604 (4 March 2014); doi: 10.1117/12.2038900
Show Author Affiliations
Satoru Suzuki, Kagawa Univ. (Japan)
Akane Ishida, Kagawa Univ. (Japan)
Pradeep K. W. Abeygunawardhana, Kagawa Univ. (Japan)
Kenji Wada, Kagawa Univ. (Japan)
Akira Nishiyama, Kagawa Univ. (Japan)
Ichiro Ishimaru, Kagawa Univ. (Japan)

Published in SPIE Proceedings Vol. 8936:
Design and Quality for Biomedical Technologies VII
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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