Share Email Print
cover

Proceedings Paper

Micro sized implantable ball lens-based fiber optic probe design
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A micro sized implantable ball lens-based fiber optic probe design is described for continuous monitoring of brain activity in freely behaving mice. A prototype uses a 500-micron ball lens and a highly flexible 350-micron-diameter fiber bundle, which are enclosed by a 21G stainless steel sheath. Several types and thickness of brain tissue, consisting of fluorescent probes such as GFP, GCaMP3 calcium indicator, are used to evaluate the performance of the imaging probe. Measured working distance is approximately 400-μm, but is long enough to detect neural activities from cortical and cerebellar tissues of mice brain.

Paper Details

Date Published: 20 February 2014
PDF: 6 pages
Proc. SPIE 8938, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV, 893813 (20 February 2014); doi: 10.1117/12.2038439
Show Author Affiliations
Jaepyeong Cha, Johns Hopkins Univ. (United States)
Jin U. Kang, Johns Hopkins Univ. (United States)


Published in SPIE Proceedings Vol. 8938:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV
Israel Gannot, Editor(s)

© SPIE. Terms of Use
Back to Top