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Proceedings Paper

Back-to-back optical coherence tomography-ultrasound probe for co-registered three-dimensional intravascular imaging with real-time display
Author(s): Jiawen Li; Teng Ma; Joseph Jing; Jun Zhang; Pranav M. Patel; K. Kirk Shung; Qifa Zhou; Zhongping Chen
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Paper Abstract

We have developed a novel integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5 mm-long rigid-part and 0.9 mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding interventional procedures. By placing the OCT ball lens and IVUS 45MHz single element transducer back-to-back at the same axial position, this probe can provide automatically co-registered, co-axial OCT-IVUS imaging. To demonstrate its capability, 3D OCT-IVUS imaging of a pig’s coronary artery in real-time displayed in polar coordinates, as well as images of two major types of advanced plaques in human cadaver coronary segments, was obtained using this probe and our upgraded system. Histology validation is also presented.

Paper Details

Date Published: 4 March 2014
PDF: 7 pages
Proc. SPIE 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, 893428 (4 March 2014); doi: 10.1117/12.2038270
Show Author Affiliations
Jiawen Li, Beckman Laser Institute (United States)
Univ. of California, Irvine (United States)
Teng Ma, The Univ. of Southern California, Los Angeles (United States)
Joseph Jing, Beckman Laser Institute (United States)
Univ. of California, Irvine (United States)
Jun Zhang, Beckman Laser Institute (United States)
Pranav M. Patel, Univ. of California, Irvine (United States)
K. Kirk Shung, The Univ. of Southern California, Los Angeles (United States)
Qifa Zhou, The Univ. of Southern California, Los Angeles (United States)
Zhongping Chen, Beckman Laser Institute (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 8934:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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