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Proceedings Paper

Application of OCT elastography for diagnosis of thyroid hydatoncus
Author(s): Zhifang Li; Xiaona Lin; Hui Li; Wei R. Chen
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Paper Abstract

In this study, we presented a method combining optical coherence tomography with wavelet differentiation method to quantify the elastic properties of tissue. Based on the optimized kernel size for 2D normalized cross-correlation, the wavelet differentiation method was used to estimate the tissue strains. The influences of the dilation parameter of wavelet on calculations of axial strain had been investigated. Experimental results suggest that the dilation parameter of 8 was selected in strain calculation for best quality of axial strain images. The method based on wavelet differentiation shows great potential for optical coherence tomography elastography. In addition, elastic properties images of thyroid with suspected cysts were depicted to distinguish benign lesions qualitatively. Thus, elastic properties imaging based on optical coherence elastography shows great promise for the detailed characterization of lesions and preliminary diagnosis of human thyroid diseases.

Paper Details

Date Published: 28 February 2014
PDF: 9 pages
Proc. SPIE 8944, Biophotonics and Immune Responses IX, 89440N (28 February 2014); doi: 10.1117/12.2038102
Show Author Affiliations
Zhifang Li, Fujian Normal Univ. (China)
Xiaona Lin, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Wei R. Chen, Fujian Normal Univ. (China)
Univ. of Central Oklahoma (United States)


Published in SPIE Proceedings Vol. 8944:
Biophotonics and Immune Responses IX
Wei R. Chen, Editor(s)

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