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Proceedings Paper

The effect of picosecond laser pulses on redox-dependent processes in mice red blood cells studied in vivo
Author(s): Olga Voronova; Tatyana Gening; Tatyana Abakumova; Aleksey Sysolyatin; Igor Zolotovskiy; Inna Antoneeva; Vladimir Ostatochnikov; Snezhanna Gening
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Paper Abstract

The study highlights the effect of different modes of in vivo laser irradiation of mice using a PFL8LA laser with λ = 1560 nm, pulse duration of 1,4•10-12 s, peak power of 3,72•103 W and average output power of 20•10-3 W on the lipid peroxidation parameters: conjugated dienes, ketodienes and conjugated trienes, malondialdehyde, Schiff bases and the activity of antioxidant enzymes - catalase, glutathione -S-transferase and superoxide dismutase in erythrocytes and plasma of mice. Two groups of mice received a total dose of 3.8 J/cm2 per group, but the 1st group was irradiated only once, while the 2nd – four times. Significant differences in the parameters of the 1st and 2nd groups indicate different effects of the irradiation modes on redox-dependent processes in red blood cells of mice.

Paper Details

Date Published: 26 February 2014
PDF: 6 pages
Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 894114 (26 February 2014); doi: 10.1117/12.2037877
Show Author Affiliations
Olga Voronova, Ulyanovsk State Univ. (Russian Federation)
Tatyana Gening, Ulyanovsk State Univ. (Russian Federation)
Tatyana Abakumova, Ulyanovsk State Univ. (Russian Federation)
Aleksey Sysolyatin, Fiber Optics Research Ctr. (Russian Federation)
Igor Zolotovskiy, Ulyanovsk State Univ. (Russian Federation)
Inna Antoneeva, Ulyanovsk State Univ. (Russian Federation)
Vladimir Ostatochnikov, Ulyanovsk State Univ. (Russian Federation)
Snezhanna Gening, Ulyanovsk State Univ. (Russian Federation)

Published in SPIE Proceedings Vol. 8941:
Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications
E. Duco Jansen; Gerald J. Wilmink; Bennett L. Ibey; Robert J. Thomas, Editor(s)

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