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Proceedings Paper

Photoacoustic microscopy of a three-dimensional arbitrary trajectory
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Paper Abstract

We have developed three-dimensional arbitrary trajectory (3-DAT) scanning, which can rapidly image vessels of interest over a large field of view (FOV) and maintain a high signal-to-noise ratio (SNR) along the depth direction. The concept of 3-DAT scanning was demonstrated by imaging a human hair within a FOV of 3.5 × 2.0 mm2. Further, we showed that hemoglobin oxygen saturation (sO2) and blood flow can be measured simultaneously. The frame rate was 67 times faster than a traditional two-dimensional raster scan. We also observed sO2 dynamics in response to a switch between systemic hyperoxia and hypoxia.

Paper Details

Date Published: 3 March 2014
PDF: 9 pages
Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 894351 (3 March 2014); doi: 10.1117/12.2037350
Show Author Affiliations
Chenghung Yeh, Washington Univ. in St. Louis (United States)
Brian Soetikno, Washington Univ. in St. Louis (United States)
Song Hu, Washington Univ. in St. Louis (United States)
Univ. of Virginia (United States)
Konstantin I. Maslov, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 8943:
Photons Plus Ultrasound: Imaging and Sensing 2014
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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