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Proceedings Paper

Rapid infrared laser sealing and cutting of porcine renal vessels, ex vivo
Author(s): Nicholas C. Giglio; Thomas C. Hutchens; William C. Perkins; Cassandra Latimer; Arlen Ward; William H. Nau; Nathaniel M. Fried
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Paper Abstract

Suture ligation with subsequent cutting of blood vessels to maintain hemostasis during surgery is time consuming and skill intensive. Energy-based, electrosurgical and ultrasonic devices are often used to replace sutures and mechanical clips to provide rapid hemostasis, and decrease surgical time. Some of these devices may create undesirably large collateral zones of thermal damage and tissue necrosis, or require separate mechanical blades for cutting. Infrared lasers are currently being explored as alternative energy sources for vessel sealing applications. In a previous study, a 1470-nm laser was used to seal vessels of 1-6 mm in diameter in 5 s, yielding burst pressures of ~ 500 mmHg. The purpose of this study was to provide faster sealing, incorporate transection of the sealed vessels, and increase the burst pressure. A 110-Watt, 1470-nm laser beam was transmitted through a fiber and beam shaping optics, producing a linear beam 3.0 mm by 9.5 mm for sealing, and 1.1 mm by 9.6 mm for cutting (FWHM). A twostep process sealed then transected ex vivo porcine renal vessels (1-8.5 mm diameter) in a bench top setup. Seal and cut times were 1.0 s each. A standard burst pressure system measured resulting seal strength, and gross and histologic thermal damage measurements were also recorded. All blood vessels tested (n = 30) were sealed and cut, with total irradiation times of 2.0 s, mean burst pressures > 1000 mmHg (compared to normal systolic blood pressure of 120 mmHg), and combined seal/collateral thermal coagulation zones of 2-3 mm. The results of this study demonstrated that an optical-based system is capable of precisely sealing and cutting a wide range of porcine renal vessel sizes, and with further development, may provide an alternative to radiofrequency and ultrasound-based vessel sealing devices.

Paper Details

Date Published: 4 March 2014
PDF: 8 pages
Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 892619 (4 March 2014); doi: 10.1117/12.2037055
Show Author Affiliations
Nicholas C. Giglio, The Univ. of North Carolina at Charlotte (United States)
Thomas C. Hutchens, The Univ. of North Carolina at Charlotte (United States)
William C. Perkins, The Univ. of North Carolina at Charlotte (United States)
Cassandra Latimer, Covidien (United States)
Arlen Ward, Covidien (United States)
William H. Nau, Covidien (United States)
Nathaniel M. Fried, The Univ. of North Carolina at Charlotte (United States)


Published in SPIE Proceedings Vol. 8926:
Photonic Therapeutics and Diagnostics X
Bernard Choi; Nikiforos Kollias; Haishan Zeng; Hyun Wook Kang; Brian J. F. Wong; Justus F. Ilgner; Guillermo J. Tearney; Kenton W. Gregory; Laura Marcu; Andreas Mandelis, Editor(s)

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