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Proceedings Paper

Modeling and experimental validation of angular radiance and distance-dependent radiance in a turbid medium
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Paper Abstract

Radiance is sensitive to the variations of tissue optical parameters, such as absorption coefficient μa, scattering coefficient μs, and anisotropy factor g. Therefore, similar to fluence, radiance can be used for tissue characterization. Compared with fluence, radiance has the advantage of offering the direction information of light intensity. Taking such advantage, the optical parameters can be determined by rotating the detector through 360 deg with only a single optode pair. Instead of the translation mode used in the fluence-based technologies, the Rotation mode has less invasiveness in the clinical diagnosis. This paper explores a new method to obtain the optical properties by measuring the distribution of light intensity in liquid phantom with only a single optode pair and the detector rotation through 360 deg. The angular radiance and distance-dependent radiance are verified by comparing experimental measurement data with Monte Carlo (MC) simulation for the short source-detector separations and diffusion approximation for the large source-detector separations. Detecting angular radiance with only a single optode pair under a certain source-detection separation will present a way for prostate diagnose and light dose calculation during the photon dynamic therapy (PDT).

Paper Details

Date Published: 4 March 2014
PDF: 8 pages
Proc. SPIE 8952, Biomedical Applications of Light Scattering VIII, 895218 (4 March 2014); doi: 10.1117/12.2036548
Show Author Affiliations
Lingling Liu, Tianjin Univ. (China)
Chenxi Li, Tianjin Univ. (China)
Huijuan Zhao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Xi Yi, Tianjin Univ. (China)
Feng Gao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Wei Meng, Tianjin Univ. (China)
Yiming Lu, Tianjin Univ. (China)


Published in SPIE Proceedings Vol. 8952:
Biomedical Applications of Light Scattering VIII
Adam Wax; Vadim Backman, Editor(s)

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