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Proceedings Paper

Time-resolved measurements in diffuse reflectance: effects of the instrument response function of different detection systems on the depth sensitivity
Author(s): Agathe Puszka; Anne Planat-Chrétien; Michel Berger; Lionel Hervé; Jean-Marc Dinten
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Paper Abstract

We demonstrate the loss of depth sensitivity induced by the instrument response function on reflectance time-resolved diffuse optical tomography through the comparison of 3 detection systems: on one hand a photomultiplier tube (PMT) and a hybrid PMT coupled with a time-correlated single-photon counting card and on the other hand a high rate intensified camera. We experimentally evaluate the depth sensitivity achieved for each detection module with an absorbing inclusion embedded in a turbid medium. The different interfiber distances of 5, 10 and 15 mm are considered. Finally, we determine a maximal depth reached for each detection system by using 3D tomographic reconstructions based on the Mellin-Laplace transform.

Paper Details

Date Published: 17 February 2014
PDF: 12 pages
Proc. SPIE 8937, Multimodal Biomedical Imaging IX, 893710 (17 February 2014); doi: 10.1117/12.2036366
Show Author Affiliations
Agathe Puszka, CEA-LETI (France)
Anne Planat-Chrétien, CEA-LETI (France)
Michel Berger, CEA-LETI (France)
Lionel Hervé, CEA-LETI (France)
Jean-Marc Dinten, CEA-LETI (France)

Published in SPIE Proceedings Vol. 8937:
Multimodal Biomedical Imaging IX
Fred S. Azar; Xavier Intes, Editor(s)

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