Share Email Print
cover

Proceedings Paper

Melanin microcavitation threshold in the near infrared
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Thresholds for microcavitation of isolated bovine and porcine melanosomes were determined using single nanosecond (ns) laser pulses in the NIR (1000 – 1319 nm) wavelength regime. Average fluence thresholds for microcavitation increased non-linearly with increasing wavelength. Average fluence thresholds were also measured for 10-ns pulses at 532 nm, and found to be comparable to visible ns pulse values published in previous reports. Fluence thresholds were used to calculate melanosome absorption coefficients, which decreased with increasing wavelength. This trend was found to be comparable to the decrease in retinal pigmented epithelial (RPE) layer absorption coefficients reported over the same wavelength region. Estimated corneal total intraocular energy (TIE) values were determined and compared to the current and proposed maximum permissible exposure (MPE) safe exposure levels. Results from this study support the proposed changes to the MPE levels.

Paper Details

Date Published: 26 February 2014
PDF: 8 pages
Proc. SPIE 8941, Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications, 894109 (26 February 2014); doi: 10.1117/12.2036287
Show Author Affiliations
Morgan S. Schmidt, Air Force Research Lab. (United States)
Paul K. Kennedy, Air Force Research Lab. (United States)
Rebecca L. Vincelette, TASC, Inc. (United States)
Kurt J. Schuster, TASC, Inc. (United States)
Gary D. Noojin, TASC, Inc. (United States)
Andrew W. Wharmby, Air Force Research Lab. (United States)
Robert J. Thomas, Air Force Research Lab. (United States)
Benjamin A. Rockwell, Air Force Research Lab. (United States)


Published in SPIE Proceedings Vol. 8941:
Optical Interactions with Tissue and Cells XXV; and Terahertz for Biomedical Applications
E. Duco Jansen; Gerald J. Wilmink; Bennett L. Ibey; Robert J. Thomas, Editor(s)

© SPIE. Terms of Use
Back to Top