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Proceedings Paper

Challenges in specificity and collection efficiency for integrated optical biosensors
Author(s): Andrea M. Armani; Simin Mehrabani; Ashley J. Maker; Cecilia Lopez; Mark C. Harrison
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Paper Abstract

While many new label-free optical sensing techniques are focusing on increasing the sensitivity or decreasing the limit of detection, the balance between sensitivity, specificity and collection efficiency are critical, particularly for detection in complex media. For example, although high Q optical resonant cavities are inherently sensitive, the collection efficiency of these devices is quite poor, particularly when compared to sensors with larger active sensing areas. By optimizing all three parameters, even further advancements in sensing technologies are possible.

Paper Details

Date Published: 7 December 2013
PDF: 8 pages
Proc. SPIE 8923, Micro/Nano Materials, Devices, and Systems, 89230F (7 December 2013); doi: 10.1117/12.2035375
Show Author Affiliations
Andrea M. Armani, Mork Family Dept. of Chemical Engineering and Materials Science, The Univ. of Southern California (United States)
Mork Family Dept. of Chemical Engineering and Materials Science, The Univ. of Southern California (United States)
Simin Mehrabani, Mork Family Dept. of Chemical Engineering and Materials Science, The Univ. of Southern California (United States)
Ashley J. Maker, Mork Family Dept. of Chemical Engineering and Materials Science, The Univ. of Southern California (United States)
Cecilia Lopez, Mork Family Dept. of Chemical Engineering and Materials Science, The Univ. of Southern California (United States)
Mark C. Harrison, Ming Hsieh Dept. of Electrical Engineering - Electrophysics, The Univ. of Southern California (United States)


Published in SPIE Proceedings Vol. 8923:
Micro/Nano Materials, Devices, and Systems
James Friend; H. Hoe Tan, Editor(s)

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