Share Email Print
cover

Proceedings Paper

Insights into esophagus tissue architecture using two-photon confocal microscopy
Author(s): Nenrong Liu; Yue Wang; Shangyuan Feng; Rong Chen
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

In this paper, microstructures of human esophageal mucosa were evaluated using the two-photon laser scanning confocal microscopy (TPLSCM), based on two-photon excited fluorescence (TPEF) and second harmonic generation (SHG). The distribution of epithelial cells, muscle fibers of muscularis mucosae has been distinctly obtained. Furthermore, esophageal submucosa characteristics with cancer cells invading into were detected. The variation of collagen, elastin and cancer cells is very relevant to the pathology in esophagus, especially early esophageal cancer. Our experimental results indicate that the MPM technique has the much more advantages for label-free imaging, and has the potential application in vivo in the clinical diagnosis and monitoring of early esophageal cancer.

Paper Details

Date Published: 30 August 2013
PDF: 5 pages
Proc. SPIE 8910, International Symposium on Photoelectronic Detection and Imaging 2013: Imaging Spectrometer Technologies and Applications, 891022 (30 August 2013); doi: 10.1117/12.2035041
Show Author Affiliations
Nenrong Liu, Fujian Normal Univ. (China)
Yue Wang, Fujian Normal Univ. (China)
Shangyuan Feng, Fujian Normal Univ. (China)
Rong Chen, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 8910:
International Symposium on Photoelectronic Detection and Imaging 2013: Imaging Spectrometer Technologies and Applications
Lifu Zhang; Jianfeng Yang, Editor(s)

© SPIE. Terms of Use
Back to Top