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Proceedings Paper

Topical photodynamic therapy with 5-ALA in the treatment of arsenic-induced skin tumors
Author(s): Sigrid Karrer; Rolf-Markus Szeimies; Michael Landthaler
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Paper Abstract

A case of a 62-year-old woman suffering from psoriasis who was treated orally with arsenic 25 years ago is reported. The cumulative dose of arsenic trioxide was 800 mg. Since 10 years ago arsenic keratoses, basal cell carcinomas, Bowen's disease and invasive squamous cell carcinomas mainly on her hands and feet have developed, skin changes were clearly a sequence of arsenic therapy. Control of disease was poor, her right little finger had to be amputated. Topical photodynamic therapy with 5-aminolevulinic acid was performed on her right hand. Clinical and histological examinations 6 months after treatment showed an excellent cosmetic result with no signs of tumor residue.

Paper Details

Date Published: 1 March 1995
PDF: 4 pages
Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203453
Show Author Affiliations
Sigrid Karrer, Univ. Regensburg (Germany)
Rolf-Markus Szeimies, Univ. Regensburg (Germany)
Michael Landthaler, Univ. Regensburg (Germany)


Published in SPIE Proceedings Vol. 2371:
5th International Photodynamic Association Biennial Meeting
Denis A. Cortese, Editor(s)

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