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Proceedings Paper

Tumor-localizing fluorescent diagnostic agents without phototoxicity: HAT-D01
Author(s): Takeshi Takemura; Shiro Umeuchi; Susumu Nakajima; Isao Sakata
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Paper Abstract

In order to develop tumor-localizing fluorescent diagnostic agents without phototoxicity, various heterodimers linked by some spacers between a chlorine derivative and its Mn or Cu complex were synthesized. The representative agent of them was named HAT-DO1 and has a molecular formula of m-phthalyl-{[13,17-bispropanoic acid-3-ethenyl-8-formylethylidene-7- hydroxy-2,7,12,18-tetramethyl-porphyrinate]-manganese (III)]}-(3'-ethenyl-8'- formylethylidene-7'-hydroxy-2',7',12',18'-tetramethyl-porphine-13',17'- bispropanoyl aspartic acid)-bishydrazone.

Paper Details

Date Published: 1 March 1995
PDF: 5 pages
Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203442
Show Author Affiliations
Takeshi Takemura, Hokkaido Univ. (Japan)
Shiro Umeuchi, Hokkaido Univ. (Japan)
Susumu Nakajima, Asahikawa Medical College (Japan)
Isao Sakata, Toyo Hakka Co. Ltd. (Japan)


Published in SPIE Proceedings Vol. 2371:
5th International Photodynamic Association Biennial Meeting
Denis A. Cortese, Editor(s)

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