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Proceedings Paper

Dark-field microspectroscopic analysis of gold nanorods in spiral Ganglion neurons
Author(s): J. Yong; W. G. A. Brown; K. Needham; B. A. Nayagam; A. Yu; S. L. McArthur; P. R. Stoddart
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Paper Abstract

Heterogeneous samples of spiral ganglion neuron primary cells were incubated with gold nanorods in order to investigate the photothermal processes induced by exposure to 780 nm laser light. Dark-field microspectroscopy was used to analyze the distribution and spectrum of nanorods in the neurons. The scattering data showed a typical gold nanorod spectrum, while a shift in the peak position suggested changes in the refractive index of the nanorod environment. The relationship between gold nanorods distribution and local temperature has also been examined with an open pipette microelectrode placed in the surrounding bath of the neurons. These temperature measurements confirm that the gold nanorods provide efficient localized heating under 780 nm laser exposure.

Paper Details

Date Published: 7 December 2013
PDF: 9 pages
Proc. SPIE 8923, Micro/Nano Materials, Devices, and Systems, 89234R (7 December 2013); doi: 10.1117/12.2033767
Show Author Affiliations
J. Yong, Swinburne Univ. of Technology (Australia)
W. G. A. Brown, Swinburne Univ. of Technology (Australia)
K. Needham, The Univ. of Melbourne (Australia)
B. A. Nayagam, The Univ. of Melbourne (Australia)
A. Yu, Swinburne Univ. of Technology (Australia)
S. L. McArthur, Swinburne Univ. of Technology (Australia)
P. R. Stoddart, Swinburne Univ. of Technology (Australia)

Published in SPIE Proceedings Vol. 8923:
Micro/Nano Materials, Devices, and Systems
James Friend; H. Hoe Tan, Editor(s)

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