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Proceedings Paper

Mechanism of photodynamic therapy (PDT): investigation of sensitizer dose and light dose-rate effects
Author(s): Takeshi Takemura; Shiro Umeuchi; Susumu Nakajima; Isao Sakata
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Paper Abstract

The thresholds in sensitizer concentration and in light dose rate for PDT effects have been examined on the basis of a chemical reaction. The examination revealed that there exists basically no thresholds of drug and light dose-rate effects in PDT, but apparently there does. Also it was suggested that PDT effects depend largely on peak power of laser and not so largely on the total joule. And for PDT the use of pulse laser with relatively high peak power is better than the use of the lower one, especially cw laser.

Paper Details

Date Published: 1 March 1995
PDF: 4 pages
Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203374
Show Author Affiliations
Takeshi Takemura, Hokkaido Univ. (Japan)
Shiro Umeuchi, Hokkaido Univ. (Japan)
Susumu Nakajima, Asahikawa Medical College (Japan)
Isao Sakata, Toyo Hakka Co. Ltd. (Japan)

Published in SPIE Proceedings Vol. 2371:
5th International Photodynamic Association Biennial Meeting
Denis A. Cortese, Editor(s)

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