Share Email Print
cover

Proceedings Paper

Characteristics of chiral and racemic ketoprofen drugs using terahertz time-domain spectroscopy
Author(s): Yong Du; Jianjun Liu; Zhi Hong
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Absorption spectra of chiral S-(+)- and racemic RS-ketoprofen pharmaceutical molecules in crystalline form were recorded in the terahertz region between 6 and 66 cm-1 (0.2 ~ 2.0 THz) by using time-domain terahertz spectroscopic (THz-TDS) measurement. Different distinctive absorption features were observed which are strikingly sensitive to the change of subtle conformational structures within such isostructural crystal molecules. The results suggest that the THz-TDS technique can be definitely used for distinguishing between chiral and racemic compounds in pharmaceutical and biological fields.

Paper Details

Date Published: 23 August 2013
PDF: 6 pages
Proc. SPIE 8909, International Symposium on Photoelectronic Detection and Imaging 2013: Terahertz Technologies and Applications, 89090M (23 August 2013); doi: 10.1117/12.2033147
Show Author Affiliations
Yong Du, China Jiliang Univ. (China)
Jianjun Liu, China Jiliang Univ. (China)
Zhi Hong, China Jiliang Univ. (China)


Published in SPIE Proceedings Vol. 8909:
International Symposium on Photoelectronic Detection and Imaging 2013: Terahertz Technologies and Applications
Marco Rahm; Konstantin Vodopyanov; Wei Shi; Cunlin Zhang, Editor(s)

© SPIE. Terms of Use
Back to Top