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Proceedings Paper

Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266nm laser beam
Author(s): T. Alexandru; M. L. Pascu; B. Danko; V. Nastasa; M. Boni; A. Militaru; I. R. Andrei; A. Staicu; A. Hunyadi; A. Armada; M. Viveiros; L. Amaral
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Paper Abstract

Phenothiazine exposed to white light or UV radiation undergoes a variety of reactions that result in the degradation of the parental compound and the formation of new species. Chlorpromazine exposed to the 266 nm laser beam of given energy levels yielded species derived from it, whose number increased with the exposure duration. At distinct time intervals the irradiation products were evaluated by spectrophotometry between 200-1500 nm, Thin Layer Chromatography, and for antimicrobial activity of Chlorpromazine against different test organisms such as Staphylococcus aureus.

Paper Details

Date Published: 10 June 2013
PDF: 7 pages
Proc. SPIE 8882, ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III, 88820T (10 June 2013); doi: 10.1117/12.2032666
Show Author Affiliations
T. Alexandru, National Institute for Lasers, Plasma and Radiation Physics (Romania)
Univ. of Bucharest (Romania)
M. L. Pascu, National Institute for Lasers, Plasma and Radiation Physics (Romania)
COST of the European Commission (Belgium)
B. Danko, Univ. of Szeged (Hungary)
COST of the European Commission (Belgium)
V. Nastasa, National Institute for Lasers, Plasma and Radiation Physics (Romania)
M. Boni, National Institute for Lasers, Plasma and Radiation Physics (Romania)
Univ. of Bucharest (Romania)
A. Militaru, National Institute for Lasers, Plasma and Radiation Physics (Romania)
Univ. of Bucharest (Romania)
COST of the European Commission (Belgium)
I. R. Andrei, National Institute for Lasers, Plasma and Radiation Physics (Romania)
A. Staicu, National Institute for Lasers, Plasma and Radiation Physics (Romania)
A. Hunyadi, Univ. of Szeged (Hungary)
COST of the European Commission (Belgium)
A. Armada, Univ. Nova de Lisboa (Portugal)
M. Viveiros, Univ. Nova de Lisboa (Portugal)
L. Amaral, Univ. Nova de Lisboa (Portugal)
COST of the European Commission (Belgium)


Published in SPIE Proceedings Vol. 8882:
ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III
Valentin I. Vlad, Editor(s)

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