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Proceedings Paper

The DNA assembler for next generation sequencers
Author(s): Jan Twardowski; Robert Nowak
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Paper Abstract

The aim of this paper is new application for de novo assembly DNA reads produced by next generation sequencers. The algorithm based on de Bruin graph is proposed, it uses both DNA strands: coding and complementary. The read errors are corrected. The repetitive sequences longer than read are correctly reconstructed in some cases. The application in client-server architecture was developed and tested on pseudo-random sequences and reads generated from genomes of model organisms.

Paper Details

Date Published: 25 October 2013
PDF: 6 pages
Proc. SPIE 8903, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013, 890317 (25 October 2013); doi: 10.1117/12.2032637
Show Author Affiliations
Jan Twardowski, Warsaw Univ. of Technology (Poland)
Robert Nowak, Warsaw Univ. of Technology (Poland)


Published in SPIE Proceedings Vol. 8903:
Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013
Ryszard S. Romaniuk, Editor(s)

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