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Proceedings Paper

Dual mode fibre bundle confocal endomicroscopy: combining reflectance and fluorescence imaging
Author(s): Michael Hughes; Vasiliki Simaiaki; Tou Pin Chang; Guang-Zhong Yang
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Paper Abstract

Commercial endomicroscopes operate in fluorescence mode only and so require the application of contrast agents. As an alternative, we describe a fibre bundle confocal endomicroscope which acquires simultaneous and co-registered fluorescence and reflectance mode images. A combination of polarisation selection and refractive index matching is used to minimise back-reflections from the fibre bundle. We show preliminary results from the system using phantoms and tissue samples.

Paper Details

Date Published: 17 June 2013
PDF: 5 pages
Proc. SPIE 8797, Advanced Microscopy Techniques III, 879708 (17 June 2013); doi: 10.1117/12.2032551
Show Author Affiliations
Michael Hughes, Imperial College London (United Kingdom)
Vasiliki Simaiaki, Imperial College London (United Kingdom)
Tou Pin Chang, Imperial College London (United Kingdom)
Guang-Zhong Yang, Imperial College London (United Kingdom)

Published in SPIE Proceedings Vol. 8797:
Advanced Microscopy Techniques III
Emmanuel Beaurepaire; Peter T. C. So, Editor(s)

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