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Proceedings Paper

Hydroxyapatite thin films synthesized by Pulsed Laser Deposition onto titanium mesh implants for cranioplasty applications
Author(s): L. Duta; G. E. Stan; A. C. Popescu; G. Socol; F. M. Miroiu; I. N. Mihailescu; A. Ianculescu; I. Poeata; A. Chiriac
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Paper Abstract

We report on the synthesis of advanced nanostructured hydroxyapatite thin films onto 3D titanium (Ti) mesh substrates by Pulsed Laser Deposition method. Morphological and structural investigations as well as pull-out tests proved the stoichiometric transfer of crystalline hydroxyapatite (HA) films along with their good adherence. In vivo tests were performed on 12 patients (six with simple Ti mesh, six with Ti mesh biofunctionalized with HA). The tomodensitometry analysis of the cranial control scans evidenced the process of osseogenesis. For four patients with implanted HA/Ti mesh structures, the modification of the value obtained on Hounsfield scale was observed at the level of implant, proving the progress of osseointegration. We conclude that the structures exhibit excellent bonding strength and functionality, and are suitable for neurosurgical applications.

Paper Details

Date Published: 10 June 2013
PDF: 7 pages
Proc. SPIE 8882, ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III, 888208 (10 June 2013); doi: 10.1117/12.2032338
Show Author Affiliations
L. Duta, National Institute for Lasers, Plasma and Radiation Physics (Romania)
G. E. Stan, National Institute of Materials Physics (Romania)
A. C. Popescu, National Institute for Lasers, Plasma and Radiation Physics (Romania)
G. Socol, National Institute for Lasers, Plasma and Radiation Physics (Romania)
F. M. Miroiu, National Institute for Lasers, Plasma and Radiation Physics (Romania)
I. N. Mihailescu, National Institute for Lasers, Plasma and Radiation Physics (Romania)
A. Ianculescu, Politehnica Univ. of Bucharest (Romania)
I. Poeata, Gr. T. Popa Univ. of Medicine and Pharmacy (Romania)
A. Chiriac, Gr.T. Popa Univ. of Medicine and Pharmacy (Romania)


Published in SPIE Proceedings Vol. 8882:
ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III
Valentin I. Vlad, Editor(s)

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