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Proceedings Paper

Portable multispectral imaging system for oral cancer diagnosis
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Paper Abstract

This study presents the portable multispectral imaging system that can acquire the image of specific spectrum in vivo for oral cancer diagnosis. According to the research literature, the autofluorescence of cells and tissue have been widely applied to diagnose oral cancer. The spectral distribution is difference for lesions of epithelial cells and normal cells after excited fluorescence. We have been developed the hyperspectral and multispectral techniques for oral cancer diagnosis in three generations. This research is the third generation. The excited and emission spectrum for the diagnosis are acquired from the research of first generation. The portable system for detection of oral cancer is modified for existing handheld microscope. The UV LED is used to illuminate the surface of oral cavity and excite the cells to produce fluorescent. The image passes through the central channel and filters out unwanted spectrum by the selection of filter, and focused by the focus lens on the image sensor. Therefore, we can achieve the specific wavelength image via fluorescence reaction. The specificity and sensitivity of the system are 85% and 90%, respectively.

Paper Details

Date Published: 28 September 2013
PDF: 6 pages
Proc. SPIE 8845, Ultrafast Imaging and Spectroscopy, 884515 (28 September 2013); doi: 10.1117/12.2023304
Show Author Affiliations
Yao-Fang Hsieh, National Central Univ. (Taiwan)
Mang Ou-Yang, National Chiao Tung Univ. (Taiwan)
Cheng-Chung Lee, National Central Univ. (Taiwan)

Published in SPIE Proceedings Vol. 8845:
Ultrafast Imaging and Spectroscopy
Zhiwen Liu, Editor(s)

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