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Proceedings Paper

Recognition as a challenging label-free optical sensing system
Author(s): Günter Gauglitz
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Paper Abstract

Optical biosensors are increasingly used in application areas of environmental analysis, healthcare and food safety. The quality of the biosensor’s results depends on the interaction layer, the detection principles, and evaluation strategies, not only on the biopolymer layer but also especially on recognition elements. Using label-free optical sensing, non-specific interaction between sample and transducer has to be reduced, and the selectivity of recognition elements has to be improved. For this reason, strategies to avoid non-specific interaction even in blood and milk are discussed, a variety of upcoming recognition is given. Based on the classification of direct optical detection methods, some examples for the above mentioned applications are reviewed. Trends as well as advantages of parallel multisport detection for kinetic evaluation are also part of the lecture.

Paper Details

Date Published: 3 May 2013
PDF: 10 pages
Proc. SPIE 8774, Optical Sensors 2013, 87740I (3 May 2013); doi: 10.1117/12.2021797
Show Author Affiliations
Günter Gauglitz, Eberhard Karls Univ. Tübingen (Germany)


Published in SPIE Proceedings Vol. 8774:
Optical Sensors 2013
Francesco Baldini; Jiri Homola; Robert A. Lieberman, Editor(s)

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