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Proceedings Paper

LGR5 expressing cells of hair follicle as potential targets for antibody mediated anti-cancer laser therapy
Author(s): Boris V. Popov
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Paper Abstract

Near infrared laser immunotherapy becomes now a new promising research field to cure the patients with cancers. One of the critical limitation in medical application of this treatment is availability of the specific markers for delivery of laser-sensitive nanoparticles. When coupled to antibodies to the cancer stem cells markers these nanoparticles may be delivered to the cancer tissue and mediate the laser induced thermolysis of the cancer stem cells that initiate and drive growth of cancer. This paper addresses the Lgr5 cell surface marker mediating the Wnt/β-catenin signal transduction as a potential target for anti-cancer laser immunotherapy of skin cancers.

Paper Details

Date Published: 26 February 2013
PDF: 8 pages
Proc. SPIE 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV, 86990O (26 February 2013); doi: 10.1117/12.2018463
Show Author Affiliations
Boris V. Popov, Institute of Cytology (Russian Federation)


Published in SPIE Proceedings Vol. 8699:
Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV
Valery V. Tuchin; Elina A. Genina; Vladimir L. Derbov; Igor V. Meglinski, Editor(s)

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