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Proceedings Paper

Cell array fabrication by plasma nanotexturing
Author(s): Dimitrios Kontziampasis; Athanasia Bourkoula; Panagiota Petrou; Angeliki Tserepi; Sotirios Kakabakos; Evangelos Gogolides
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Paper Abstract

Cell behavior (i.e. attachment, proliferation, etc.) on nanostructured surfaces is currently a hot topic throughout the scientific community. However, studies often show diverging results due to differences in cells, local surface chemistry, and nanotopography fabrication methods. In this study, we use Oxygen plasma etching to both randomly nanotexture a PMMA surface and change its surface chemistry. We find that 3T3 cells behave quite differently on flat PMMA surfaces as compared to nanotextured ones, showing an on-off attachment behavior. Work is under progress to exploit this effect allowing selective cell capturing, and creation of cell arrays in adjacent plasma-nanotextured/smooth areas using a stencil mask during etching.

Paper Details

Date Published: 28 May 2013
PDF: 10 pages
Proc. SPIE 8765, Bio-MEMS and Medical Microdevices, 87650B (28 May 2013); doi: 10.1117/12.2017894
Show Author Affiliations
Dimitrios Kontziampasis, National Ctr. for Scientific Research Demokritos (Greece)
Athanasia Bourkoula, National Ctr. for Scientific Research Demokritos (Greece)
Panagiota Petrou, National Ctr. for Scientific Research Demokritos (Greece)
Angeliki Tserepi, National Ctr. for Scientific Research Demokritos (Greece)
Sotirios Kakabakos, National Ctr. for Scientific Research Demokritos (Greece)
Evangelos Gogolides, National Ctr. for Scientific Research Demokritos (Greece)


Published in SPIE Proceedings Vol. 8765:
Bio-MEMS and Medical Microdevices
Angeliki Tserepi; Manuel Delgado-Restituto; Eleni Makarona, Editor(s)

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