Share Email Print
cover

Proceedings Paper

Hybrid interfaces for a new class of optical biosensors
Author(s): L. De Stefano; A. Caliò; J. Politi; P. Giardina; I. Redina; I. Rea
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Interfaces play a key role in optical biosensor fabrication: biological molecules need to be integrated with inorganic transducers, both electrical and optical, preserving their functions and specificity. Single DNA stands, proteins, enzymes, and antibodies must be blocked on surface by absorption or covalently, depending on different chemistry used. In case of proteins and antibodies, also orientation of biological molecules is very important. In this work, we present our results on a biological passivation procedure that employs hydophobins, small amphiphilic proteins. Since these proteins complex with sugars in nature, we also suggest their utilization as functional layer in optical biosensor for glucose.

Paper Details

Date Published: 3 May 2013
PDF: 4 pages
Proc. SPIE 8774, Optical Sensors 2013, 87741G (3 May 2013); doi: 10.1117/12.2017615
Show Author Affiliations
L. De Stefano, CNR, Istituto per la Microelettronica e Microsistemi (Italy)
A. Caliò, CNR, Istituto per la Microelettronica e Microsistemi (Italy)
Univ. degli Studi di Napoli Federico II (Italy)
J. Politi, CNR, Istituto per la Microelettronica e Microsistemi (Italy)
Univ. degli Studi di Napoli Federico II (Italy)
P. Giardina, Univ. degli Studi di Napoli Federico II (Italy)
I. Redina, CNR, Istituto per la Microelettronica e Microsistemi (Italy)
I. Rea, CNR, Istituto per la Microelettronica e Microsistemi (Italy)


Published in SPIE Proceedings Vol. 8774:
Optical Sensors 2013
Francesco Baldini; Jiri Homola; Robert A. Lieberman, Editor(s)

© SPIE. Terms of Use
Back to Top