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Proceedings Paper

3D laser optoacoustic ultrasonic imaging system for preclinical research
Author(s): Sergey A. Ermilov; André Conjusteau; Travis Hernandez; Richard Su; Vyacheslav Nadvoretskiy; Dmitri Tsyboulski; Fatima Anis; Mark A. Anastasio; Alexander A. Oraevsky
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Paper Abstract

In this work, we introduce a novel three-dimensional imaging system for in vivo high-resolution anatomical and functional whole-body visualization of small animal models developed for preclinical or other type of biomedical research. The system (LOUIS-3DM) combines a multi-wavelength optoacoustic and ultrawide-band laser ultrasound tomographies to obtain coregistered maps of tissue optical absorption and acoustic properties, displayed within the skin outline of the studied animal. The most promising applications of the LOUIS-3DM include 3D angiography, cancer research, and longitudinal studies of biological distribution of optoacoustic contrast agents (carbon nanotubes, metal plasmonic nanoparticles, etc.).

Paper Details

Date Published: 4 March 2013
PDF: 5 pages
Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810N (4 March 2013); doi: 10.1117/12.2008811
Show Author Affiliations
Sergey A. Ermilov, TomoWave Labs. Inc. (United States)
André Conjusteau, TomoWave Labs. Inc. (United States)
Travis Hernandez, TomoWave Labs. Inc. (United States)
Richard Su, TomoWave Labs. Inc. (United States)
Vyacheslav Nadvoretskiy, TomoWave Labs. Inc. (United States)
Dmitri Tsyboulski, TomoWave Labs. Inc. (United States)
Fatima Anis, Washington Univ. in St. Louis (United States)
Mark A. Anastasio, Washington Univ. in St. Louis (United States)
Alexander A. Oraevsky, TomoWave Labs. Inc. (United States)


Published in SPIE Proceedings Vol. 8581:
Photons Plus Ultrasound: Imaging and Sensing 2013
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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