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Proceedings Paper

Imaging in biological tissues by means of diffraction tomography with photon density waves
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Paper Abstract

In biological tissues it is possible to generate photon density waves with wavelength below 5 cm. When these kind of waves encounter optical inhomogeneities with diameters in the millimeter and centimeter range, typical scattering effects occur. These scattering effects can be compared to the well known effect of ultrasound scattering. Ultrasound gets scattered at regions with different compressibility and density, while photon density waves are scattered at regions with different absorption and scattering coefficient. In this study, analytical solutions for the time dependent photon diffusion equation are used to estimate photon density wave diffraction effects caused by spherical optical inhomogeneities. The detectability of tumors and hemorrhages in the brain, based on the diffraction pattern generated by these heterogeneities, is discussed in detail.

Paper Details

Date Published: 31 January 1995
PDF: 11 pages
Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); doi: 10.1117/12.200865
Show Author Affiliations
Andreas H. Hielscher, Rice Univ. and Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Frank K. Tittel, Rice Univ. (United States)
Steven L. Jacques, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)

Published in SPIE Proceedings Vol. 2326:
Photon Transport in Highly Scattering Tissue
Sigrid Avrillier; Britton Chance; Gerhard J. Mueller; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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